INVESTIGATION OF THE PROMISING REPURPOSED, COMPUTATIONAL, AND ANTICANCER CANDIDATES TO CO-DELIVER WITH CABAZITAXEL FOR HORMONAL-RESISTANCE PROSTATE CANCER

red prairie spy apple The novel antimicrotubular taxane called cabazitaxel was developed to avoid the primary mechanism of resistance for docetaxel, the first-line treatment for patients with hormone-resistant prostate cancer (HRPC).However, its ability to increase the survival rate for HRPC is limited to a few months, and cabazitaxel-resistant pro

Background and objectives: In children, acute infection is the most common cause of visits in the primary care or emergency department.In 2002, criteria for diagnostics of pediatric sepsis were published, and then revised in 2016 as “life-threatening organ dysfunction due to a dysregulated host response to infection”.In the pathophysiol

Utilizing supervised machine learning algorithms to develop a surveillance and response system based on symptoms of diarrhoea, contingent on the Support Vector Machine pink chiclets gum (SVM) to predict the probable disease using labelled data.Diarrhoea is amongst the top ten diseases which kill.A prototype system is developed based on the SVM algo

Recently, there has been a growing interest in utilizing surface texture to enhance the tribological properties of sliding components.Particularly noteworthy is the application of tool vibration at ultrasonic frequencies for efficiently generating surface textures.This study focuses on generating surface texture on the end surface of a stainless st

The article presents the results of the effect of treating tubers and above-ground parts of the Kuzovok potato variety with SiO2 and Mo nanoparticles on morphometric parameters and biochemical composition.It was found that treating seed potato tubers with SiO2 0.18, Mo 0.045 g/kg increased germination energy on the 6th day regardless of the nanopar